The 20th International Congress of Collateral Diseases | Academician Ge Junbo: The treatment of pan-vascular diseases cannot be done by “blind people touching the elephant”, and a holistic thinking is required

[ad_1]

“Data from the “China Cardiovascular Health and Disease Report 2022″ state that there are about 17 million people with cerebrovascular disease, about 20 million people with coronary heart disease, and more than 45.3 million people with lower limb arterial disease. These diseases closely related to blood vessels will lead to death and disability and severe complications such as amputation.” On February 24, at the 20th International Congress of Collateral Diseases, Academician Ge Junbo of the Chinese Academy of Sciences from Zhongshan Hospital Affiliated to Fudan University gave an academic speech titled “Panvascular Disease: Enlightenment and Future Strategies” The report points out that the burden of vascular-related diseases in China is serious, and these data emphasize the importance of paying attention to vascular health in national public health work.

Academician Ge Junbo gave an academic report titled “Panvascular Disease: Enlightenment and Future Strategies”

Atherosclerosis is a systemic pathological change, a group of systemic vascular diseases that mainly harms important organs such as the heart, brain, kidneys, and limbs. Because atherosclerotic disease affects the entire vascular network, the REACH registry highlights the intertwined nature of vascular disease. It is worth noting that coronary artery disease (CAD), peripheral artery disease (PAD) and cerebrovascular disease coexist. Reinforces the need for comprehensive panvascular management of these diseases. Based on the above, Academician Ge Junbo mentioned in the report the concept of pan-vascular medicine from “vascular tree” to “vascular network” and then to “pan-vascular”. The concept of “pan-vascular disease” is to understand and manage the systemic risks of patients with atherosclerosis. It provides an overall solution. This holistic and overall view of a disease is similar to the theory of collateral disease in traditional Chinese medicine proposed by Academician Wu Yiling of the Chinese Academy of Engineering.

The proposal of the concept of “pan-vascular disease” breaks through the limitations of single disease research, allowing clinicians to evaluate patients holistically. They no longer “treat the head when there is a headache and the feet when there is pain”, but look at the patient as a whole and use the system to Sexual, continuous and coordinated treatment, rehabilitation and follow-up can jointly control the incidence of pan-vascular diseases.

Academician Ge Junbo mentioned that long-term studies in the past have shown that inflammation, LDL cholesterol levels and blood sugar are the main factors affecting pan-vascular diseases. Therefore, the importance of controlling hypertension, hyperlipidemia, and hyperglycemia in the treatment of pan-vascular diseases has become a widespread academic concern. consensus.

Early research by Ge Junbo’s team found that vascular stress and mechanical stress are key factors leading to the development of atherosclerosis; in addition, other unknown factors such as plaque stability may also lead to the occurrence of cardiovascular events. He also emphasized that residual risks, including inflammatory, thrombotic and metabolic pathways, also contribute to the recurrence of adverse cardiovascular events, but these influencing factors are often not recognized or addressed in clinical practice.

“Judging from the current medical model, if the patient has a stroke, the neurologist will be in charge; if the patient has a heart attack, the cardiologist will take over; just like the blind touching the elephant, each blind person represents a different medical specialty and touches the elephant. part of the body and draw one-sided conclusions about what they touched.” Academician Ge Junbo pointed out.

Academician Ge Junbo said that in the management of pan-vascular diseases, traditional knowledge can no longer predict the full consequences of the disease. In the future, the integration of information including patient characteristics, clinical manifestations, biomarkers, and radiomics will become a trend. “Integrating this individual information into a comprehensive platform, and through big data analysis, a personalized pan-vascular index can be derived to address these challenges.”

Academician Ge Junbo emphasized: “In the past four years, China has begun to establish more than 100 pan-vascular centers and collect data from these pan-vascular centers by establishing local data sets and cloud data sets, which will support clinical management and research and integrate pan-vascular Medicine is translated into clinical practice. It is expected that in the future these pan-vascular centers will have more data to share with the world. As the field develops, the integration of artificial intelligence and genomics will play a key role in the development of personalized interventions, marking This is an important step forward in precision medicine in the field of pan-vascular health!”

[ad_2]

Source link