Academician Jia Weiping: Integrating traditional Chinese and Western medicine to fully promote the transformation of diabetes treatment into full-course health management

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Inherit the essence, innovate and break through, transform the results, and go global. On February 24, the 20th International Collateral Congress was held grandly in Shijiazhuang, Hebei. At the meeting, Professor Jia Weiping, academician of the Chinese Academy of Engineering, director of the Shanghai Diabetes Research Institute, and Professor of the Sixth People’s Hospital of Shanghai Jiao Tong University, delivered a keynote speech titled “Prevalence Status and Prevention and Control Strategies of Diabetes and Chronic Complications in China” during the academic report session of the main forum. The report focuses on the incidence and prevention strategies of chronic complications of diabetes, emphasizing that diabetes is a complex system project, and the integration of traditional Chinese and Western medicine can fully promote the transformation of diabetes treatment into full-course health management.

Academician Jia Weiping gave an academic report at the meeting

Academician Jia Weiping pointed out that among various metabolic diseases, diabetes is the fastest-growing, most harmful, and most urgent health problem in my country. The current prevention and control of diabetes in our country is represented by three “1/3”. The awareness rate of diabetes is relatively low, only 1/3, and diagnosed diabetes accounts for only 38% of the 125 million diabetic patients; the treatment rate for diagnosed diabetes is only 1/3; for patients receiving treatment, it is also Only 1/3 of people have their blood sugar levels under control.

The awareness, treatment and control rates are low, seriously threatening human health. Data show that every year, about 9.484 million people in my country suffer from blindness, kidney failure, stroke, myocardial infarction, and amputation due to diabetes complications, and the average life span is shortened by 9 years.

In order to understand to the greatest extent the population prevalence characteristics of multiple complications in urban and rural diabetic patients in different regions, assess the status of cardiometabolic risk control and the current implementation of standardized diagnosis and treatment, in 2017 Academician Jia Weiping led the study of diabetic retinopathy, nephropathy, and vascular disease. and a nationwide survey of neuropathy. The results show that the prevalence of diabetic retinopathy has reached 16.3%. Based on this, it is estimated that about 19.5 million diabetic patients in my country suffer from diabetic retinopathy. “Fortunately, 80% are non-serious vision-threatening lesions. Through metabolic control, blood sugar can be lowered.” , lowering blood pressure and regulating blood lipids can delay its development, which suggests that most diabetic patients in my country can prevent their vision loss through regular screening and active intervention.” Academician Jia Weiping pointed out that another survey showed that among diabetic patients in my country, The prevalence of chronic kidney disease reaches 32.7%, which indicates that diabetes-related chronic kidney disease will also be a focus of diabetes prevention and treatment in the future.

Academician Jia Weiping believes that currently, there are a large number of patients with chronic diseases at the grassroots level, which is one of the main battlefields for diabetes prevention and control. In terms of diabetes treatment, it is not only necessary to follow the clinical standard guidelines of Western medicine, but it is also very important to include traditional Chinese medicine prevention and treatment of diabetes in grassroots guidelines. Research has found that for the prevention and management of diabetes, the traditional Chinese medicine Jinlida Granules combined with metformin is more effective and has been included in the “National Guidelines for the Prevention, Treatment and Management of Diabetes at the Grassroots Level (2022)”.

In the report, Academician Jia Weiping systematically reviewed a large number of clinical studies conducted on Jinlida Granules. A clinical study conducted by Tong Xiaolin, an academician of the Chinese Academy of Sciences, including 192 patients with type 2 diabetes, showed that for patients whose blood sugar still does not reach the standard after taking a stable dose of metformin, the addition of Jinlida granules can further reduce glycated hemoglobin (HbA1c) by 0.92%. , lower fasting blood sugar and 2-hour postprandial blood sugar, significantly improve pancreatic β-cell function index, improve symptoms such as thirst, fatigue, constipation, etc. It is also highly safe and has potential therapeutic advantages in slowing down or preventing complications. Further research results show that for patients with HbA1c>8.5% and age>60 years old, Jinlida Granules are more effective in reducing HbA1c and fasting blood sugar and improving insulin resistance.

On the basis of the above-mentioned studies, the results of another meta-analysis (a total of 1810 patients) conducted by the team of Academician Tong Xiaolin and including 15 randomized controlled clinical trials (RCTs) in my country showed that compared with the use of hypoglycemic drugs alone, the combined use of antidiabetic drugs is more effective. Lida Granules can further reduce fasting blood sugar, 2-hour postprandial blood sugar and HbA1c in patients with type 2 diabetes, while improving pancreatic islet function and reducing weight.

Academician Jia Weiping also introduced the “randomized, double-blind, controlled clinical study on the impact of Jinlida Granules on blood sugar fluctuations in newly diagnosed patients with type 2 diabetes” that he led. The results showed that in terms of improving blood sugar fluctuations, compared with the control group, the standard deviation of blood sugar levels of patients in the Jinlida Granule group was significantly reduced after treatment, and the time within the blood sugar target range (TIR) ​​increased by 23.2% after treatment, reaching TIR control targets recommended by domestic and foreign guidelines.

In addition, Academician Jia Weiping also mentioned that another innovative traditional Chinese medicine Tongluo Mingmu Capsule developed based on the theory of meridian “Sunluo-Microcirculation” has the functions of removing blood stasis and unblocking collaterals, replenishing qi and nourishing yin, stopping bleeding and improving eyesight. Research has confirmed its The total effective rate in treating diabetic retinopathy is 61%. It can correct glucose metabolism disorders, protect retinal capillaries, protect optic nerve cells, improve Qi collateral function, and has good safety.

Finally, Academician Jia Weiping emphasized that diabetes is a complex system project. While understanding the general treatment plan for diabetes, we must also know the characteristics of each stage of the disease, make good use of the combination of traditional Chinese and Western medicine, and make every effort to promote the transformation of diabetes treatment into full-course health management.

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