There are these traditional Chinese medicine wisdom behind the naming of this medicine…

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In response to the epidemic, the recommended anti-epidemic drugs at the national level have always been the focus of everyone’s attention.

Recently, the General Office of the National Health and Medical Commission and the General Department of the State Administration of Traditional Chinese Medicine released the “Diagnosis and Treatment Plan for Novel Coronavirus Infection (Trial Version 10)” (hereinafter referred to as “the 10th version”). In the part of traditional Chinese medicine treatment, several Chinese patent medicines such as Lianhua Qingwen and Huoxiang Zhengqi are continuously recommended.

Taking Lianhua Qingwen as an example, this is the seventh time since the outbreak that it has been recommended by the national program for the treatment of new coronavirus infection, thus further confirming the safety and applicability of the drug as a family standing antiviral Chinese patent medicine.

In fact, long before the epidemic, Lianhua Qingwen was deeply trusted by the masses and had a solid reputation. Not long ago, Lianhua Qingwen won the “Beijing Evening News Readers’ Recommended Family Standing Medicine Selection” in the “2022 Beijing Evening News Readers’ Recommended Family Standing Medicine Selection”. Standing Drugs” list.

Behind the various honors, what is the subtlety of Lianhua Qingwen?

The classic prescription inherits the millennium epidemic drug experience

The subtlety of Lianhua Qingwen might as well start from the name. Many people are very curious, why “Lianhua” was chosen instead of “Lotus” in the name of Lianhua Qingwen?

In fact, one of the commonly used methods of naming Chinese patent medicines is the abbreviation + function + dosage form of the two main medicines. The “Lian” and “Hua” in the name of “Lianhua Qingwen” come from the two representative medicinal flavors of “Forsythia” and “Honeysuckle” in the formula. The medicine has the functions of clearing away the plague and detoxification, clearing the lungs and expeling heat, so it is named Lianhua Qingwen.

It is worth noting that behind Lianhua Qingwen’s prescription is the inheritance and innovation of traditional Chinese medicine anti-epidemic drug experience for thousands of years. It is understood that the Lianhua Qingwen prescription consists of forsythia, honeysuckle, ephedra, Mianma Guanzhong, isatid root, gypsum, menthol, patchouli, rhodiola rosea, houttuynia cordata, rhubarb, fried bitter almonds, licorice 13 Flavored drug composition.

Among them, ephedra, almonds, gypsum, and licorice are the classic prescriptions in “Treatise on Febrile and Miscellaneous Diseases” – Maxing Shigan Decoction. This prescription has always been respected as the “first prescription for reducing fever” in traditional Chinese medicine. It is suitable for treating unresolved external evils. And the stage when the evil heat blocks the lungs, this is the most important stage of the disease’s outcome. Later dynasties of Chinese medicine have continued to develop this prescription. As long as the pathogenesis of stagnant heat in the lung meridian is closed and the lung qi is not ventilated, bronchitis, asthma, pneumonia and other diseases can be treated with this prescription. It can be seen that its scope of application is very wide.

In the Qing Dynasty, Chinese medicine ushered in a new revolution in anti-epidemic. Yinqiao powder in “Warm Disease Tiaodian” written by Wu Jutong can be regarded as one of the revolutionary achievements of the febrile disease school in fighting epidemics. Lianhua Qingwen is also included in this prescription, namely forsythia, honeysuckle, mint, etc. Honeysuckle dissipates heat and detoxifies the surface, forsythia clears heat and detoxifies the surface, mint is pungent and cools, clears and sharpens the head, and together play a role in pungent coolness, clearing away heat and detoxifying.

In addition, Lianhua Qingwen also innovatively added rhubarb, Huoxiang and rhodiola. Huoxiang aromatizes dampness and protects the spleen and stomach, and rhodiola regulates immunity and strengthens righteousness. In particular, the use of rhubarb has inherited the principle of “never tire of getting down early, never tire of getting down frequently, and do everything possible to drive away evil spirits” in Wu Youke’s “On the Plague”.

Obviously, Lianhua Qingwen’s prescription contains two thousand years of anti-epidemic experience and wisdom of traditional Chinese medicine, and has made outstanding contributions to protecting people’s health in modern epidemics such as “SARS”, “A flu” and “COVID-19”. Safety and effectiveness can stand the test of history and reality.

Scientific and evidence-based contributions to the prevention and treatment of new crowns

How do good medicines work?

In the tenth version of the plan, Lianhua Qingwen is listed as the recommended drug for treating mild and medium patients in traditional Chinese medicine.

It is reported that Lianhua Qingwen is a compound preparation composed of 13 medicinal flavors. It has multi-components and multi-channels to show anti-influenza virus, new coronavirus, antibacterial, antipyretic, anti-inflammatory, cough-relieving, phlegm-reducing and other aspects of the system. effect. Since Lianhua Qingwen entered the market in 2003, it has received more than 30 program recommendations at the national level. From influenza A, influenza B, avian influenza to new coronavirus pneumonia, viral infectious major public health problems that have occurred in my country in recent years In the incident, Lianhua Qingwen played an important role. It is a representative Chinese patent medicine for the treatment of colds, flu, and new crown infections, and can be used as a standing medicine at home.

For the treatment of COVID-19 patients, the “Prospective, randomized, controlled, multi-center clinical study of Chinese medicine Lianhua Qingwen Capsules in the treatment of novel coronavirus pneumonia” jointly participated by 23 new crown-infected hospitals confirmed that Lianhua Qingwen can effectively treat COVID-19 For patients with confirmed infection and suspected patients, it shows a good trend in improving fever, fatigue, and cough symptoms, shortening the duration of symptoms, improving the proportion of lung CT improvement, clinical treatment effect, and reducing the rate of serious illness.

The study “Lianhua Qingwen has anti-viral and anti-inflammatory effects on the new coronavirus” published in the mainstream journal “Pharmacological Research” in the international pharmacology field confirmed that Lianhua Qingwen plays a role in inhibiting virus replication and inhibiting the expression of inflammatory factors in host cells. The role of anti-new coronavirus activity. The latest research also found that Lianhua Qingwen showed a stable in vitro antiviral effect on Alpha, Beta, and Delta and other mutant strains.

In addition, Meta-analysis shows that the application of Lianhua Qingwen has good safety. A Meta-analysis of adverse reactions in 217 clinical studies of Lianhua Qingwen from its launch to February 2021 involves the treatment of influenza, respiratory infections, and pneumonia with this variety. , New Coronary Pneumonia and many other diseases, the results showed that Lianhua Qingwen or combined with conventional drugs, compared with the conventional drug group, the overall incidence of adverse reactions was lower (P<0.001), and there was no liver and kidney function damage related to Lianhua Qingwen. The main adverse reactions of Lianhua Qingwen found in this meta-analysis are consistent with the adverse reactions such as nausea, diarrhea, vomiting, rash, and itching monitored by the National Center for Adverse Drug Reaction Monitoring.

It is reported that since the outbreak of the new crown virus infection, Lianhua Qingwen has played an important role in the prevention and treatment of 30 countries and regions including Russia, Canada, Brazil, Indonesia, Kuwait, and Cambodia, and has been included in the white list of anti-epidemic drugs by Cambodia, Uzbekistan, and other countries. Home treatment plan for mild patients. Lianhua Qingwen has been sold in 30 countries, benefiting countless patients infected with the new coronavirus around the world from traditional Chinese medicine.

High cost performance and strong market demand

How to make good medicine more accessible? As the market’s demand for COVID-19 drugs becomes more prominent, the availability of drugs has also attracted much attention. Cost-effective medicines mean further improvement in accessibility.

In fact, in daily life, when people buy medicines, the first choice is that the medicine has a good effect, and the cost performance is often a very important dimension of consideration.

Lianhua Qingwen itself is a medical insurance catalog product, and its price is also very cost-effective. It is reported that during the H1N1 influenza pandemic in 2009, ten domestic influenza A hospitals conducted an evidence-based medical study of “Lianhua Qingwen Capsules for the treatment of H1N1 influenza A”, and the patients in the test group were treated according to the standard treatment every day The patients in the control group were given oseltamivir. The results of the study showed that there was no difference between Lianhua Qingwen and oseltamivir in terms of antiviral effect. Lianhua Qingwen is excellent in relieving flu symptoms, especially in reducing fever and relieving symptoms such as cough, headache, muscle aches and fatigue. In particular, it should be pointed out that the daily treatment cost of Lianhua Qingwen is only 1/8 of that of oseltamivir.

For the treatment of mild and common types of new crowns, Lianhua Qingwen Capsules are taken 4 capsules at a time, 3 times a day, and the daily cost is 7.4 yuan; Lianhua Qingwen Granules are taken 1 bag at a time, 3 times a day, daily The cost of taking it is about 8.9 yuan, and the course of treatment for 7 to 10 days can basically relieve the symptoms effectively. The price of only tens of yuan for a course of treatment is also an important reason why it is so popular among the public.

Obviously, good medicine, good effect, and more advantageous price are the reasons why Lianhua Qingwen can be favored by the public and become a representative drug for the treatment of respiratory viral infectious diseases and a leading brand of Chinese patent medicine for cold medicine in the retail market. “Exquisite”.

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